The Global Information Infrastructure and Networking Symposium (GIIS) consists of an interrelated set of technical, policy, and social issues implicit in the development of national and international (global) information infrastructures and networks. GIIS aims at identifying and promoting the exchange of knowledge on these interrelated issues and provides liaison to bodies in the global society, technical fora and international standards. GIIS2025 follows the success of the precedent editions and intends to promote interdisciplinary conference sessions to discuss, build and further the use of national and international information infrastructures and networks. The conference also aims at providing a forum for the participants to broaden their professional contacts and for technical discussions and interactions on specific information infrastructure and networking topics. The program of GIIS2025 will include invited talks and keynotes, paper presentations, tutorials, panels, and discussion sessions.